We are analyzing computational models of nerve fibers to understand how they respond to high-frequency stimulation waveforms. Our goal is to use mathematical modeling and engineering techniques to improve existing models and contribute to the improvement of electrical neuromodulation therapies.
We are developing computational models of noninvasive electrical stimulation to design strategies that are able to reach spinal cord structures using surface electrodes. Modulating the activity of nerve fibers or neurons in the spine is being used for pain relief in people with chronic pain.
Spinal cord stimulation (SCS) is a well-established therapy to relieve pain in subjects with chronic pain. In this therapy, electrical currents are delivered to the dorsal column (DC) of the spinal cord via electrodes implanted in the epidural space.