Spinal cord stimulation

Slow Inactivation of Fast Sodium Channels Mediates Accommodation of Nerve Fiber Activity During Kilohertz-Frequency Spinal Cord Stimulation

An automatic method for detection of evoked events in the brain during spinal cord stimulation

Parkinson’s disease (PD) is a neurodegenerative brain disorder that mainly affects the elderly population and currently has no cure, only palliative treatments. Recently, spinal cord stimulation (SCS) showed great promise in the treatment of certain …

Noninvasive Electrical Stimulation of the Spinal Cord for Pain Management

We are developing computational models of noninvasive electrical stimulation to design strategies that are able to reach spinal cord structures using surface electrodes. Modulating the activity of nerve fibers or neurons in the spine is being used for pain relief in people with chronic pain.

Fondecyt 11190822: Model-based analysis of a novel modality of spinal cord stimulation for the treatment of chronic pain

Spinal cord stimulation (SCS) is a well-established therapy to relieve pain in subjects with chronic pain. In this therapy, electrical currents are delivered to the dorsal column (DC) of the spinal cord via electrodes implanted in the epidural space.

Quantification of Dorsal Column Fiber Responses in a Model of Kilohertz-Frequency Spinal Cord Stimulation

Introduction Kilohertz-frequency spinal cord stimulation (KHF-SCS) was recently proposed as a paresthesia-free treatment for persons with chronic pain that is potentially more effective than conventional (̃50 Hz) SCS. In SCS, the applied electrical …

Quantitative Analysis of Kilohertz-Frequency Neurostimulation

Mainstream electrical stimulation therapies, e.g., spinal cord stimulation (SCS) and deep brain stimulation, use pulse trains that are delivered at rates no higher than 200 Hz. In recent years, stimulation of nerve fibers using kilohertz-frequency …

Duke University/Stryker Corp. Model-based Analysis and Desing of Therapy